SayanFUEL STIM

SayanFUEL - STIM is Yamamoto® Nutrition's innovative pre-workout designed to bring your performance to a higher level and composed of 12 different ingredients at the service of your performance. SayanFUEL contains L-citrulline, Beta-alanine, Pomegranate extract, L-tyrosine, Alpinia galanga extract, caffeine anhydrous, a proprietary blend of S7 plant extracts, green tea extract, proanthocyanidins, vitamin B6, thiamine and vitamin B12. It is therefore the "stimulating" version of Sayan, because it contains caffeine, and is designed for those who need a real energy boost, both physical and mental, to tackle all training, even the most intense .

The SayanFUEL formula exploits the synergistic action of many extracts to maximize performance, give a boost to your energy and at the same time stimulate the production of Nitric Oxide, to maximize the pump muscular. It's real fuel for your workouts.

What does the SayanFUEL formula consist of in detail?

Here in detail are all the ingredients used to develop SayanFUEL and their specific action:

L-citrulline – Citrulline is a non-essential amino acid that is very useful for athletes : acting as a precursor of arginine, it improves the supply of blood and oxygen to the muscles, stimulating the production of Nitric Oxide, also with effects on the muscle pump. As a result, citrulline increases endurance and supports performance during physical activity. Citrulline can also help reduce muscle soreness and fatigue after physical activity, because it reduces the build-up of lactic acid in the muscles.

Beta-alanine – Beta-alanine is a precursor to carnosine, a compound that buffers the accumulation of lactate in muscle tissue. Taking Beta-alanine therefore helps to delay the feeling of fatigue and muscle soreness and improves performance in high intensity exercises. The International Society of Sports Nutrition (ISSN) believes that supplementation with Beta-alanine acts as an intracellular pH buffer, is safe and can improve performance in physical exercise, especially in the case of high intensity and short duration. Furthermore, this supplement is also capable of easing neuromuscular fatigue as well.

Pomegranate Extract – it is a concentrate of antioxidants and vitamins, useful for supporting energy (both physical and mental), slowing down the oxidative process and improving blood flow , reducing the feeling of fatigue and thus making performances more efficient.

L-tyrosine – this amino acid, a precursor of several hormones, is known for supporting the synthesis of several neurotransmitters in the brain, such as dopamine and norepinephrine. In this way it can carry out an adaptogenic action in case of stress and at the same time improve the attention span.

Alpinia Galanga extract – obtained from the tuber of Alpinia galanga, a herbaceous plant of the zingiberaceae family, this plant extract allows you to maintain a high mental focus and acts in synergy with caffeine, optimizing activity dopaminergic of the latter. It is in fact able to enhance the effect of vigilance and concentration given by caffeine, supporting cognitive performance.

Caffeine Anhydrous – Caffeine is among the best-known supplements for supporting alertness and performance, used largely to optimize explosive energy. The active ingredient of caffeine allows you to improve concentration, reactivity and attention span.

S7® –S7® is a combination of seven plant-based ingredients that stimulate nitric oxide and, as studies have shown, can turn on the body's Nitric Oxide production system. body. S7® is completely plant-based and nitrate-free, and is designed to let you experience the benefits of nitric oxide without side effects, so you can better focus on your performance. In a double-blind, peer-reviewed acute study, S7 demonstrated a 230% increase in circulating nitric oxide in the blood compared to baseline in participants after a single 50 mg dose. S7 has been clinically proven to help increase nitric oxide levels with daily and long-term use. In a 90-day, double-blind, peer-reviewed study, this ingredient demonstrated a 53% increase in circulating nitric oxide levels in the blood with once-daily supplementation compared to placebo for support long-term treatment of nitric oxide.

Proanthocyanidins – also called tannins, are a group of natural substances that belong to the polyphenol family and the flavonoid subgroup. They have demonstrated anti-inflammatory, antioxidant, cardioprotective and immunomodulatory properties.

Vitamin B6 – this B vitamin plays a role in the metabolism of amino acids, fatty acids and sugars and contributes to the formation of various hormones, white and red blood cells. It also has the fundamental role of forming an immune barrier in defense against diseases, stimulating brain functions and preventing aging.

Thiamine – also called vitamin B1, is involved above all in the metabolism of carbohydrates: it plays an important role in the mechanism of transformation of glucose into energy.

Vitamin B12 – also known as Cobalamin, participates in the metabolism of amino acids, nucleic acids and fatty acids. It is essential in the production of red blood cells and in the formation of bone marrow. It also promotes the transformation of nutrients into energy and can reduce stress and increase good mood.

Scientific References

Harty PS, Zabriskie HA, Erickson JL, Molling PE, Kerksick CM, Jagim RI. Multi-ingredient pre-workout supplements, safety implications, and performance outcomes: a brief review. J Int Soc Sports Nutr. 2018 Aug 8;15(1):41. doi: 10.1186/s12970-018-0247-6. PMID: 30089501; PMCID: PMC6083567.

Boris V. Nemzer, Christoph Centner, Noemi Wiessler, Zb Pietrzkowski, John M. Hunter, Bruno Fink &Daniel König, A Double-blind, Placebo-controlled, Randomized, longitudinal study on the effects of a plant-based dietary supplement on Nitric Oxide and Mitochondrial metabolic activity, Journal of Food Research; Vol. 10, No. 2; 202

Hoffman JR, Varanoske A, Stout JR. Effects of _β_-Alanine Supplementation on Carnosine Elevation and Physiological Performance. Adv Food Nutr Res. 2018;84:183-206. doi: 10.1016/bs.afnr.2017.12.003. Epub 2018 Jan 8. PMID: 29555069.

Hobson RM, Saunders B, Ball G, Harris RC, Salt C. Effects of _β_-alanine supplementation on exercise performance: a meta-analysis. Amino Acids. 2012 Jul;43(1):25-37. doi: 10.1007/s00726-011-1200-z. Epub 2012 Jan 24. PMID: 22270875; PMCID: PMC3374095.

Guest NS, VanDusseldorp TA, Nelson MT, Grgic J, Schoenfeld BJ, Jenkins NDM, Arent SM, Antonio J, Stout JR, Trexler ET, Smith-Ryan AE, Goldstein ER, Kalman DS, Campbell BI. International society of sports nutrition position stand: caffeine and exercise performance. J Int Soc Sports Nutr. 2021 Jan 2;18(1):1. doi: 10.1186/s12970-020-00383-4. PMID: 33388079; PMCID: PMC7777221.

Burke LM. Caffeine and sports performance. Appl Physiol Nutr Metab. 2008 Dec;33(6):1319-34. doi: 10.1139/H08-130. PMID: 19088794.

Allerton TD, Proctor DN, Stephens JM, Dugas TR, Spielmann G, Irving BA. l-Citrulline Supplementation: Impact on Cardiometabolic Health. Nutrients. 2018 Jul 19;10(7):921. doi: 10.3390/nu10070921. PMID: 30029482; PMCID: PMC6073798.

Asgary S, Keshvari M, Sahebkar A, Sarrafzadegan N. Pomegranate Consumption and Blood Pressure: A Review. Curr Pharm Des. 2017;23(7):1042-1050. doi: 10.2174/1381612822666161010103339. PMID: 27748197.